An underground market for unlicensed weight-loss drugs is being driven by social media fitness personalities and sellers on messaging platforms, according to recent findings.
Retatrutide, which remains in clinical trials, is being advertised by online personalities for its alleged fat-burning effects. Followers are urged to contact these accounts privately for source information, while also receiving discount codes.
Separately, a flourishing market exists on messaging services, where groups with thousands of members share “before and after” photos, administration instructions and assertions of rapid UK delivery. Vendors market the drug there before redirecting buyers to other platforms for purchases.
Retatrutide is an experimental injectable developed by US drugmaker Eli Lilly. The drug affects three intestinal hormones – glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide and glucagon. Preliminary studies suggest it could assist patients lose up to a quarter of their total weight. Referred to as the “triple G”, the drug is being promoted online as the next Ozempic.
However, physicians and pharmacists have cautions that the distribution of what is still an unapproved drug in the United Kingdom is a cause for concern and could result in individuals administering substances of unknown origin.
Some experts said the popularity for retatrutide could be connected to the increasing cost of approved slimming products such as Mounjaro.
Marketing the unapproved drug on social media or Telegram is illegal in the United Kingdom, as it is an unapproved medication that cannot be promoted or supplied for personal consumption under the Human Medicines Regulations 2012.
Some content creators try to circumvent the rules by referring to the drug as a “research chemical” or describing it as “not for human consumption”. Retatrutide is not a controlled drug, but advertising and distribution can still breach medicines, advertising, and consumer regulations, potentially leading to penalties, prosecution or prison.
According to the social media company, the platform has removed problematic material and banned associated hashtags and search suggestions. The company stated it was committed to maintaining the service secure and investing in enhancing enforcement strategies.
Research also found groups with up to 9,000 participants marketing retatrutide using Telegram's integrated search feature, which operates like a online catalog. Typing “retatrutide” immediately displays channels with numerous of users, filled with images of weight loss, positive reviews and detailed guides for mixing or administering at residence.
Within moments of entering one community, a seller posted WhatsApp details, where most purchases occur. The seller sent an instruction manual and promised shipping within 48 hours. When questioned whether the substance was authentic, one seller responded: “You can’t be sure.” Another shared a photo of a alleged laboratory certificate. None asked about body mass, health issues or previous experience.
Within these communities, messages show black plastic parcels with Royal Mail stickers, claiming to contain new batches. One communication stated: “It took eight of us to load them this morning.”
Customers can select between powder vials, prepared at home with sterile water, or ready-to-use pens typically sold at 160 pounds for 20mg. When asked how long a pen should last, sellers give contradictory responses ranging from a few weeks to “depends on your body”.
A representative for Telegram stated it actively moderated dangerous content on its service including content that promoted the “misuse of controlled medications”. The company noted that it removed “millions of pieces of harmful content each day”.
“Individuals are administering substances they cannot confirm. Although the research behind this drug is sound, these digital versions may not include what they advertise,” said Jason Murphy, the director of pharmaceutical services at Chemist4U.
Dr Crystal Wyllie of Asda Online Doctor linked the surge in interest to recent cost increases for approved weight-loss medications such as Mounjaro. “With costs rising, patients are turning to social media. But fake treatments are extremely risky. You can’t be certain what’s inside or whether the environment they were made in was sterile,” she explained.
Her staff has previously encountered individuals harmed by self-injection from unverified sources. “We recognize the frustration, but purchasing from messaging apps or WhatsApp is taking chances with your health,” said Wyllie. “These materials could be contaminated or incorrectly dosed.”
A spokesperson from Eli Lilly said the substance was in third stage clinical trials and had not been reviewed or approved by any government authority globally. “Consequently at this point no one can sell [it] for personal consumption,” they explained, adding that any product “falsely representing itself as a company investigational substance not yet approved … may subject users to potentially serious medical dangers”.
Tech enthusiast and digital strategist with a passion for exploring innovative solutions and sharing actionable insights.